Science as the foundation, digital as care
Relieve
pain
Improving the
outpatient
care pathway
Relieve anxiety
Our mission
To design, develop, and deliver digital therapy solutions validated by robust and independent clinical studies, serving both caregivers and patients.
To digitalize care and make it accessible to all by providing a concrete, effective, and secure response to the management of pain and anxiety.
To provide healthcare professionals with reliable, practical tools that simplify the patient care pathway.
Our ambition
Enhancing the management of pain and anxiety.
Providing innovative, alternative, and complementary solutions to conventional therapy.
Improving the care pathway from both organizational and economic perspectives.
Our experience
6
years of clinical
experience
6
Robust, controlled, and independent clinical studies
100+
Healthcare institutions
using the solution
Bliss DTx,
our immersive and immediate
sedation solution
Bliss DTx, a Class I CE-marked medical device, is an immersive solution designed to support patients before, during, and after painful and/or anxiety-inducing medical procedures.
It is used either as an adjunct to or as a substitute for traditional pharmacological products and medical gases.
The solution immerses patients in sound and visual environments that engage their capacities and place them in a modified state of consciousness, significantly reducing the perceived level of pain.
Complementary to medication, Bliss DTx is designed as a universal solution accessible to all patients, without social or language barriers.
The environments
Our clinical evidence
REVEH Study
Study objective
To evaluate the efficacy and safety of Bliss DTx compared with MEOPA* in preventing pain during bone marrow biopsy.
Primary endpoint
No significant difference in pain intensity (p = 0.26) between the MEOPA group and the Bliss DTx group.
Methodology
126 patients enrolled in a multicenter, randomized, phase III study.
Presented at
Published in 2023
p=0,26
MEOPA
n = 63
Bliss DTx
n = 63
Pain intensity assessed using the Visual Analog Scale
(VAS, 0 = no pain, 10 = worst imaginable pain)
Secondary endpoints
Physician satisfaction was significantly higher (p = 0.01) with the use of Bliss DTx compared to MEOPA.
p=0,01
MEOPA
n = 59
Bliss DTx
n = 58
No adverse events occurred during the biopsy in the group Bliss DTx.
Non-inferiority of Bliss DTx compared to MEOPA in preventing pain during bone marrow biopsies.
*MEOPA is a medical gas used for its anxiolytic and analgesic properties. It is an equimolar mixture of oxygen and nitrous oxide.
A new option in pain prevention with bliss, a therapeutic virtual reality solution in bone marrow biopsy context: Results of a French open-label multicenter randomized phase II/III study (REVEH Trial) (2021)
Bliss DTx, a medical, organizational, and economic benefit
The possible choice of local or regional anesthesia instead of general anesthesia
A direct positive impact on resource use (nursing time and cost)
Before the procedure
An alternative to the use of medical gas in pain management, without side effects
A direct positive impact on resource use (nursing time and cost)
During the procedure
Possible avoidance or reduction of recovery room admission
Faster return to the patient’s room without a stretcher
A direct positive impact on resource use (cost, nursing time, and faster turnover in the recovery room)
After the procedure
Bliss DTx,
possible applications
in pain and anxiety management
During diagnostic and sampling procedures (biopsy, lumbar puncture, etc.)
During painful and anxiety-inducing care such as dressing changes in geriatrics or in burn patients
During surgical procedures as an adjunct to local anesthesia (Port-a-Cath surgery, endovenous thermal treatment of varicose veins, etc.)
Our products in development
Endocare DTx,
our solution dedicated to endometriosis
An innovative alternative for better living with endometriosis
Endocare DTx is a new medical device based on immersive digital therapy.
It is designed to support women suffering from chronic pelvic pain related to endometriosis.
By combining sensory neurostimulation, deep relaxation, and hypnotic guidance, Endocare DTx provides an innovative, effective, and side-effect-free alternative.
The efficacy and safety of our solution have been validated in two randomized controlled clinical studies.
Our key publications
Innovation, rigor, and scientific evidence
A new option in pain prevention with bliss, a therapeutic virtual reality solution in bone marrow biopsy context: Results of a French open-label multicenter randomized phase II/III study (REVEH Trial) (2021)
Authors: Katell LE DU, Anne-Lise Septans, Frédéric Maloisel, Hélène Vanquaethem, Anna Schmitt, Marielle Le Goff, Marie Pierre Moles, Marie Zinger, Hugues Pierre Bourgeois, Mélanie Peron, Fabrice Denis, and Stéphane Bouchard
Pain Reduction With an Immersive Digital Therapeutic Tool in Women Living With Endometriosis-Related Pelvic Pain: Randomized Controlled Trial (2022)
Benjamin Merlot 1, Garance Dispersyn 2, Zoé Husson 1, Isabella Chanavaz-Lacheray 1, Thomas Dennis 1, Juliette Greco-Vuilloud 2, Maxime Fougère 2, Stéphane Potvin 3, Maryne Cotty-Eslous 2, Horace Roman 1, Serge Marchand 2
Pain Reduction With an Immersive Digital Therapeutic in Women Living With Endometriosis-Related Pelvic Pain: At-Home Self-Administered Randomized Controlled TrialPain Reduction With an Immersive Digital Therapeutic in Women Living With Endometriosis-Related Pelvic Pain: At-Home Self-Administered Randomized Controlled Trial (2023)
Authors of this article:Benjamin Merlot1 Author Orcid Image ; Valéry Elie2 Author Orcid Image ; Adrien Périgord2 Author Orcid Image ; Zoé Husson1 Author Orcid Image ; Amandine Jubert1 Author Orcid Image ; Isabella Chanavaz-Lacheray1 Author Orcid Image ; Thomas Dennis1 Author Orcid Image ; Maryne Cotty-Eslous2 Author Orcid Image ; Horace Roman1 Author Orcid Image
Our team
We are a group of experts passionate about virtual reality and its potential in healthcare.
The complementarity of our backgrounds is our strength. Epidemiologists, oncologists, angiologists, engineers, and computer scientists work together to design innovative, rigorous solutions focused on both practitioners and their patients.
By combining scientific, medical, and technological expertise, we explore new pathways to improve care through digital therapy in the fields of pain and anxiety.
